Cytologically Yours: Unknowns: 201401: Case 4 - Revision history

Seung Park at 20:10, 16 January 2014

2014-01-16T20:10:26Z

Seung Park: /* Resident Questions */

2014-01-16T20:07:16Z

‎Resident Questions

Seung Park at 20:06, 16 January 2014

2014-01-16T20:06:27Z

Seung Park at 18:47, 16 January 2014

2014-01-16T18:47:28Z

Seung Park at 18:34, 16 January 2014

2014-01-16T18:34:57Z

Stephanie Simmons at 18:29, 16 January 2014

2014-01-16T18:29:33Z

Stephanie Simmons at 18:29, 16 January 2014

2014-01-16T18:29:16Z

Stephanie Simmons: Created page with "==Cytology== CytologicallyYoursUnknowns201401-04-01.jpg CytologicallyYoursUnknowns201401-04-02.jpg CytologicallyYoursUnknowns201401-04..."

2014-01-15T19:53:46Z

Created page with "==Cytology== <gallery heights="333px" widths="333px"> CytologicallyYoursUnknowns201401-04-01.jpg CytologicallyYoursUnknowns201401-04-02.jpg CytologicallyYoursUnknowns201401-04..."

New page

==Cytology==
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← Older revision		Revision as of 20:10, 16 January 2014
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		+	==Clinical History==
		+	74 year old male with a pancreatic mass.
		+
	==Cytology==		==Cytology==
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 * Flow cytometry is helpful when lymphoma is suspected
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 ===Resident Questions===
-* <spoiler text="Diagnosis?">
+* <spoiler text="Diagnosis?">__NOGLOSSARY__
 * Lymphoma
 ** Occurs in elderly
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 * Rare tissue fragments
 </spoiler>
-* <spoiler text="Differential diagnosis?">
+* <spoiler text="Differential diagnosis?">__NOGLOSSARY__
 * Pancreatic neuroendocrine tumor
 ** Uniform, small/medium sized, round, plasmacytoid cells
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-CytologicallyYoursUnknowns201401-04-07.JPG
+CytologicallyYoursUnknowns201401-04-07.jpg
-CytologicallyYoursUnknowns201401-04-08.JPG
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← Older revision		Revision as of 18:34, 16 January 2014
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	{{Cytologically Yours}}		{{Cytologically Yours}}
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		+	[[Category:Unknowns]]

← Older revision		Revision as of 18:29, 16 January 2014
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	CytologicallyYoursUnknowns201401-04-06.jpg		CytologicallyYoursUnknowns201401-04-06.jpg
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		+
		+	===Resident Questions===
		+	* <spoiler text="Diagnosis?">
		+	* Lymphoma
		+	** Occurs in elderly
		+	** Diffuse large B cell lymphoma is the most common
		+	** Presentation includes abdominal pain and jaundice due to bile duct obstruction
		+	** Pancreatic primary lymphoma accounts for less than 0.5% of all pancreatic malignancies and 1% of extranodal lymphomas
		+	** Secondary involvement of the pancreas by lymphoma has been reported to occur in 5-30% of all lymphomas.
		+	</spoiler>
		+
		+	* <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">
		+	* Cellular specimen
		+	* Monotonous population of cells that are discohesive
		+	* Look for lymphoglandular bodies in the background
		+	* Cells will have high N/C ratios with round nuclei
		+	* Mitosis
		+	* Karryorrhexis
		+	* Lack nuclear molding
		+	* Rare tissue fragments
		+	</spoiler>
		+
		+	* <spoiler text="Differential diagnosis?">
		+	* Pancreatic neuroendocrine tumor
		+	** Uniform, small/medium sized, round, plasmacytoid cells
		+	** Cells in groups
		+	** Scant cytoplasm
		+	** Salt and pepper chromatin
		+	** Positive CD56, Synaptophysin, Chromogranin
		+	* Pancreatic duct adenocarcinoma (small cell pattern)
		+	** Generally cellular
		+	** Groups and single small/medium cells
		+	** Irregular nuclear membranes and variable cytoplasm (scant/moderate, vacuolated/dense)
		+	** Positive CEA, Cytokeratin, EMA
		+	* Lymphoepithelial cyst
		+	** Rare benign cystic lesion with lymphocytes
		+	** Most occur in male patients who are in the 5th decade
		+	** Unilocular or multilocular lined by squamous epithelium and have numerous lymphocytes
		+	** Cytology will have many lymphocytes and squamous cells
		+	** Not associated with immunosuppression
		+	* Flow cytometry is helpful when lymphoma is suspected
		+	</spoiler>
		+
		+	<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the Additional Images.</div>
		+	<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
		+	<div class="mw-collapsible-content">
		+
		+	==Additional Images==
		+	<gallery heights="500px" widths="500px">
		+	CytologicallyYoursUnknowns201401-04-07.JPG
		+	CytologicallyYoursUnknowns201401-04-08.JPG
		+	CytologicallyYoursUnknowns201401-04-09.JPG
		+	CytologicallyYoursUnknowns201401-04-10.JPG
		+	</gallery>
		+
		+	{{Cytologically Yours}}