IPLab:Lab 11:Schistosomiasis - Revision history

Seung Park: /* Images */

2013-08-30T01:46:55Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-25T04:47:44Z

‎Related IPLab Cases

Seung Park: /* Images */

2013-08-25T04:47:13Z

‎Images

Seung Park: /* Journal Articles */

2013-08-25T04:44:42Z

‎Journal Articles

Seung Park: /* Reference */

2013-08-25T04:43:53Z

‎Reference

Seung Park at 04:25, 23 August 2013

2013-08-23T04:25:54Z

Seung Park at 16:07, 21 August 2013

2013-08-21T16:07:53Z

Seung Park at 14:41, 21 August 2013

2013-08-21T14:41:22Z

Seung Park: Created page with "== Images == File:IPLab11Schistosomiasis1.jpg|This is a high-power photomicrograph of the patient's fecal specimen containing the char..."

2013-08-21T05:05:55Z

Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab11Schistosomiasis1.jpg|This is a high-power photomicrograph of the patient's fecal specimen containing the char..."

New page

== Images ==
<gallery heights="250px" widths="250px">
File:IPLab11Schistosomiasis1.jpg|This is a high-power photomicrograph of the patient's fecal specimen containing the characteristic egg of Schistosoma mansoni. Note the spine on the egg (arrow).
File:IPLab11Schistosomiasis2.jpg|This is high-power photomicrograph of the patient's fecal specimen containing another Schistosoma mansoni egg.
File:IPLab11Schistosomiasis3.jpg|This is a photomicrograph of the liver from another patient with Schistosoma mansoni. These eggs have elicited a robust inflammatory response, including a multinucleated giant cell. These lesions go on to heal by fibrosis resulting in cirrhosis and the classic "pipe-stem" fibrosis.
</gallery>

{{IPLab 11}}

[[Category: IPLab:Lab 11]]

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/2164-schistosoma PEIR Digital Library: Schistosomiasis Images]
+* [{{SERVER}}/library/index.php?/tags/2164-schistosoma PEIR Digital Library: Schistosomiasis Images]
 * [http://library.med.utah.edu/WebPath/GIHTML/GIIDX.html WebPath: Gastrointestinal Pathology]
 * [http://library.med.utah.edu/WebPath/LIVEHTML/LIVERIDX.html WebPath: Hepatic Pathology]

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 == Related IPLab Cases ==
+* [[IPLab:Lab 2:Fatty Change and Cirrhosis|Lab 2: Liver: Fatty Change and Cirrhosis]]
 {{IPLab 11}}
 [[Category: IPLab:Lab 11]]

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 === Images ===
+* [http://peir.path.uab.edu/library/index.php?/tags/2164-schistosoma PEIR Digital Library: Schistosomiasis Images]
 == Related IPLab Cases ==

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 * [http://emedicine.medscape.com/article/788867-overview eMedicine Medical Library: Emergent Management of Acute Schistosomiasis]
 * [http://www.merckmanuals.com/professional/infectious_diseases/trematodes_flukes/schistosomiasis.html Merck Manual: Schistosomiasis]
 === Images ===

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/228392-overview eMedicine Medical Library: Schistosomiasis]
 === Journal Articles ===

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 * <spoiler text="How do Schistosoma mansoni eggs cause liver pathology?">A substance released from the eggs is a direct hepatotoxin. The eggs incite a chronic granulomatous inflammatory reaction (thought to be mediated by TNFa and T-helper cells). And schistosome eggs stimulate lymphocytes to secrete lymphokines that stimulate periportal fibrosis.</spoiler>
 * <spoiler text="How does the clinical picture of S. haematobium differ from that of the other schistosomes?">S. haematobium leads to granulomatous lesions in the urinary bladder that can erode the surface epithelium and lead to hematuria. Chronic inflammation and fibrosis can lead to obstruction, hydronephrosis and ascending bacterial infections. There is also an increased risk for squamous cell carcinoma of the bladder.</spoiler>
 {{IPLab 11}}
 [[Category: IPLab:Lab 11]]

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 File:IPLab11Schistosomiasis3.jpg|This is a photomicrograph of the liver from another patient with Schistosoma mansoni. These eggs have elicited a robust inflammatory response, including a multinucleated giant cell. These lesions go on to heal by fibrosis resulting in cirrhosis and the classic "pipe-stem" fibrosis.
 </gallery>
 {{IPLab 11}}
 [[Category: IPLab:Lab 11]]

← Older revision		Revision as of 14:41, 21 August 2013
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		+	== Clinical Summary ==
		+	This 30-year-old white male was admitted to the hospital following an upper gastrointestinal hemorrhage with repeated hematemesis. On admission he was tachycardic and had orthostatic hypotension. Endoscopy revealed the presence of esophageal varices. Following fluid replacement and control of bleeding, the patient appeared well. Careful physical exam revealed a palpable spleen extending to the umbilicus. Ascites was not present. The hematocrit was 27%, the white count 12,000 with 30% eosinophils, and the platelet count 98,000. The patient denied alcohol use and had no history of hepatitis. However it was found that two years prior to admission he had worked as a Peace Corps volunteer on a fish-farming project in Ghana. He had been generally healthy while in Africa. He could recall only a fever and cough lasting two or three days, and a brief episode of fever, chills, and headache which was empirically treated as malaria, although no parasites were seen on a single peripheral smear at the time. Since his return to the U.S. eighteen months ago, he had been in good health, but had occasionally noticed some vague left upper quadrant discomfort. Examination of the stool for ova and parasites revealed a few Schistosoma mansoni eggs.
		+
	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">