IPLab:Lab 3:Chronic Peptic Ulcer - Revision history

Peter Anderson: /* Journal Articles */

2016-08-25T14:09:36Z

‎Journal Articles

2014-01-03T16:08:12Z

2013-08-30T01:27:05Z

‎Images

2013-08-21T22:22:43Z

‎Additional Resources

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‎Images

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‎Journal Articles

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‎Reference

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 === Journal Articles ===
-* Mackie DB, Gent AE.  [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491545/ Management of upper gastrointestinal haemorrhage].  ''Ann R Coll Surg Engl'' 1977 January; 59(1): 56–60.
+* Laine L.  [http://www.nejm.org/doi/10.1056/NEJMcp1514257 Upper Gastrointestinal Bleeding Due to a Peptic Ulcer.]  ''NEJM'' 2016 June 22; 374: 2367-2376.
 === Images ===

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 File:IPLab3ChronicPepticUlcer11.jpg|This is a trichrome-stained section of tissue demonstrating fibrous connective tissue scar formation (blue color) in this lesion. The surface of the ulcer is at the left-hand side of the image. There is a layer of inflammatory cells and RBCs on the surface of the ulcer.
 </gallery>
 == Study Questions ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/122-peptic_ulcer PEIR Digital Library: Peptic Ulcer Images]
+* [{{SERVER}}/library/index.php?/tags/122-peptic_ulcer PEIR Digital Library: Peptic Ulcer Images]
 * [http://library.med.utah.edu/WebPath/GIHTML/GIIDX.html#2 WebPath: Stomach Pathology]

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 * [http://peir.path.uab.edu/library/index.php?/tags/122-peptic_ulcer PEIR Digital Library: Peptic Ulcer Images]
 * [http://library.med.utah.edu/WebPath/GIHTML/GIIDX.html#2 WebPath: Stomach Pathology]
 {{IPLab 3}}
 [[Category: IPLab:Lab 3]]

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 === Images ===
+* [http://peir.path.uab.edu/library/index.php?/tags/122-peptic_ulcer PEIR Digital Library: Peptic Ulcer Images]
 === Related IPLab Cases ===

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/181753-overview eMedicine Medical Library: Peptic Ulcer Disease]
 === Journal Articles ===

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 * <spoiler text="Why is infection with Helicobacter pylori considered to be a significant risk factor for development of peptic ulcers?">''H. pylori'' is found in 90-100% of cases. It is thought that the ''H. pylori'' produce urease, leading to ammonia production and that they also produce a protease that breaks down glycoproteins in the mucus which forms the protective coat on the gastric mucosa.</spoiler>
 * <spoiler text="What cells make of the inflammatory reaction at the base of this chronic ulcer?">The base of this chronic ulcer has a granulomatous inflammatory reaction composed of lymphocytes, macrophages, fibroblasts, and endothelial cells. This is in contrast to the acute inflammatory reaction at the surface of the ulcer due to irritation from the acid and gastric contents.</spoiler>
 {{IPLab 3}}
 [[Category: IPLab:Lab 3]]