IPLab:Lab 7:Bronchogenic Carcinoma - Revision history

Seung Park at 16:25, 3 January 2014

2014-01-03T16:25:25Z

Seung Park: /* Images */

2013-08-30T01:41:00Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-23T19:59:22Z

‎Related IPLab Cases

Seung Park: /* Images */

2013-08-23T19:58:15Z

‎Images

Seung Park: /* Journal Articles */

2013-08-23T19:56:48Z

‎Journal Articles

Seung Park: /* Reference */

2013-08-23T19:54:10Z

‎Reference

Seung Park at 04:21, 23 August 2013

2013-08-23T04:21:40Z

Seung Park at 15:38, 21 August 2013

2013-08-21T15:38:09Z

Seung Park at 14:34, 21 August 2013

2013-08-21T14:34:55Z

Seung Park: Created page with "== Images == File:IPLab7Bronchogenic1.jpg|This is a gross photograph of bronchogenic carcinoma. The large tumor mass can be seen adjac..."

2013-08-21T02:01:46Z

Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab7Bronchogenic1.jpg|This is a gross photograph of bronchogenic carcinoma. The large tumor mass can be seen adjac..."

New page

== Images ==
<gallery heights="250px" widths="250px">
File:IPLab7Bronchogenic1.jpg|This is a gross photograph of bronchogenic carcinoma. The large tumor mass can be seen adjacent to the bronchus (1). Note that the epithelial surface of the bronchus is rough and irregular (2). The first branch off the right main stem bronchus is partially occluded by the thickened mucosa and submucosa (3).
File:IPLab7Bronchogenic2.jpg|This is a low-power photomicrograph of bronchus showing normal mucosa (1) with transition to carcinoma (2). Note the bronchial cartilage (3) and the invasion of tumor through the entire wall of the bronchus with tumor extending to the serosal surface (4).
File:IPLab7Bronchogenic3.jpg|This is a photomicrograph of bronchus with ulcerated mucosal surface on the right (1). The submucosa is completely filled with tumor down to the cartilage (2).
File:IPLab7Bronchogenic4.jpg|This is a higher-power photomicrograph of bronchus with the ulcerated mucosal surface on the right and tumor underneath.
File:IPLab7Bronchogenic5.jpg|This is a higher-power photomicrograph of the mucosal surface (right) with an area of hemorrhage (arrow) and underlying tumor (left).
File:IPLab7Bronchogenic6.jpg|This is a photomicrograph of tumor from an area of invasion with compression of fibrous stroma and focal necrosis.
File:IPLab7Bronchogenic7.jpg|This is a high-power photomicrograph showing cytologic detail of the tumor with an area of necrosis (1) and a more differentiated area with keratin pearl formation (2).
File:IPLab7Bronchogenic8.jpg|This is a high power photomicrograph of tumor with an area of central necrosis (arrow).
File:IPLab7Bronchogenic9.jpg|This high-power photomicrograph of tumor shows the cytologic detail of a less-differentiated area of neoplasm with cellular anaplasia.
</gallery>

{{IPLab 7}}

[[Category: IPLab:Lab 7]]

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/27-lung/112-carcinoma PEIR Digital Library: Lung Carcinoma Images]
+* [{{SERVER}}/library/index.php?/tags/27-lung/112-carcinoma PEIR Digital Library: Lung Carcinoma Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html WebPath: Pulmonary Pathology]

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 == Related IPLab Cases ==
+* [[IPLab:Lab 7:Lip SCC|Lab 7: Lip: Squamous Cell Carcinoma]]
 {{IPLab 7}}
 [[Category: IPLab:Lab 7]]

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 === Images ===
+* [http://peir.path.uab.edu/library/index.php?/tags/27-lung/112-carcinoma PEIR Digital Library: Lung Carcinoma Images]
 == Related IPLab Cases ==

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 === Journal Articles ===
+* Hyer JD, Silvestri G.  [http://www.ncbi.nlm.nih.gov/pubmed/10763092 Diagnosis and staging of lung cancer].  ''Clin Chest Med'' 2000 Mar;21(1):95-106, viii-ix.
 === Images ===

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/279960-overview eMedicine Medical Library: Non-Small Cell Lung Cancer]
 === Journal Articles ===

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 File:IPLab7Bronchogenic9.jpg|This high-power photomicrograph of tumor shows the cytologic detail of a less-differentiated area of neoplasm with cellular anaplasia.
 </gallery>
 == Study Questions ==

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 # serotonin, associated with the carcinoid syndrome. The incidence of clinically significant syndromes related to these factors ranges from 1 to 10% of all lung cancer patients. Any one of the histologic types of tumors may occasionally produce any one of the hormones, but tumors producing ACTH and ADH are predominantly small cell carcinomas and those producing hypercalcemia are mostly squamous cell tumors.</spoiler>
 * <spoiler text="What is the prognosis for patients with bronchiogenic carcinoma?">The clinical course is somewhat variable but in general the prognosis is poor with a 5 year survival of approximately 9%.</spoiler>
 {{IPLab 7}}
 [[Category: IPLab:Lab 7]]

← Older revision		Revision as of 14:34, 21 August 2013
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		+	== Clinical Summary ==
		+	This 55-year-old white male had a long history of emphysema and a 60-70 pack-year smoking history. He was in his usual state of health until about one month before admission, at which time he developed increasing dyspnea on exertion. At the same time, his sputum increased from two tablespoons to half a cup of yellow blood-streaked sputum a day. Chest x-ray showed a right hilar mass. Sputum cytology revealed abnormal cells that were "positive for malignancy." He later developed pneumonia and fever. The patient expired soon thereafter.
		+
		+	== Autopsy Findings ==
		+	Significant findings included advanced carcinoma of the right main stem bronchus with extension across the carina to produce obstruction of the left main stem bronchus. There was left lower lobe pneumonia and left upper lobe atelectasis. Extensive metastases were present in regional lymph nodes as well as the pericardium, left atrium, and right kidney.
		+
	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">