IPLab:Lab 8:Poliomyelitis - Revision history

Seung Park: /* Virtual Microscopy */

2014-01-03T16:30:39Z

‎Virtual Microscopy

2014-01-03T16:29:38Z

2013-08-30T01:42:41Z

‎Images

2013-08-26T00:51:33Z

‎Clinical Summary

2013-08-24T01:21:23Z

‎Related IPLab Cases

2013-08-24T01:21:11Z

‎Images

2013-08-24T01:19:16Z

‎Journal Articles

2013-08-24T01:17:51Z

‎Reference

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2013-08-21T15:48:07Z

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 == Virtual Microscopy ==
 <peir-vm>IPLab8Polio</peir-vm>
 == Study Questions ==

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 File:IPLab8Polio5.jpg|This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.
 </gallery>
 == Study Questions ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/2149-polio PEIR Digital Library: Polio Images]
+* [{{SERVER}}/library/index.php?/tags/2149-polio PEIR Digital Library: Polio Images]
 * [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#7 WebPath: CNS Pathology: Acquired and Congenital Degenerative Diseases]

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 == Clinical Summary ==
-Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/cmm). He died on the third hospital day.
+Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/mm³). He died on the third hospital day.
 == Autopsy Findings ==

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 * [http://peir.path.uab.edu/library/index.php?/tags/2149-polio PEIR Digital Library: Polio Images]
 * [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#7 WebPath: CNS Pathology: Acquired and Congenital Degenerative Diseases]
 {{IPLab 8}}
 [[Category: IPLab:Lab 8]]

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 === Journal Articles ===
+* Alexander L, Birkhead G, Guerra F, Helms C, Hinman A, Katz S, LeBaron CW, Modlin J, Murphy TV; National Vaccine Advisory Committee-Advisory Committee on Immunization Practices Joint Working Group; Centers for Disease Control and Prevention.  [http://www.ncbi.nlm.nih.gov/pubmed/15583093 Ensuring preparedness for potential poliomyelitis outbreaks: recommendations for the US poliovirus vaccine stockpile from the National Vaccine Advisory Committee (NVAC) and the Advisory Committee on Immunization Practices (ACIP)].  ''Arch Pediatr Adolesc Med'' 2004 Dec;158(12):1106-12.
 === Images ===

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/967950-overview eMedicine Medical Library: Pediatric Poliomyelitis]
 === Journal Articles ===

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 * <spoiler text="How does poliovirus cause cell death?">Poliovirus replicates inside neurons and causes lysis of the cell.</spoiler>
 * <spoiler text="What is the mode of transmission of poliovirus?">Poliovirus is an enterovirus that is usually acquired from contaminated water. It has been effectively controlled by immunization; however, among the nonimmune it causes a nonspecific gastroenteritis. In a small fraction of the vulnerable population, it can invade the nervous system where it attacks lower motor neurons.</spoiler>
 {{IPLab 8}}
 [[Category: IPLab:Lab 8]]