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File:IPLab10Blasto10.jpg|This is a very high-power photomicrograph showing Blastomyces organisms stained with PAS. Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background.
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== Virtual Microscopy ==
=== H&E ===
<peir-vm>IPLab10Blasto_HE</peir-vm>
=== PAS ===
<peir-vm>IPLab10Blasto_PAS</peir-vm>
== Study Questions ==
* <spoiler text="What is the route of infection of Blastomyces?">Blastomyces is acquired by inhalation of infectious spores from the soil.</spoiler>
* <spoiler text="Blastomyces has a restricted geographical distribution in the US. What regions are endemic?">In the United States, infection is usually limited to areas along the Mississippi, Ohio, and St. Lawrence Rivers, and along the Great Lakes.</spoiler>
* <spoiler text="What groups of people are at increased risk for Blastomyces?">Those exposed to dust--construction workers exposed to dust from construction sites, hunters and outdoors people who walk in dusty areas, and farm workers.</spoiler>
* <spoiler text="What is the usual clinical manifestation of Blastomyces infection?">Most patients get a pyogranulomatous pneumonia. However, Blastomyces can spread outside the lungs to the skin, bones, and prostate.</spoiler>
== Additional Resources ==
=== Reference ===
* [http://emedicine.medscape.com/article/354067-overview eMedicine Medical Library: Imaging in Thoracic Blastomycosis]
* [http://emedicine.medscape.com/article/296870-overview eMedicine Medical Library: Blastomycosis]
* [http://www.merckmanuals.com/professional/infectious_diseases/fungi/blastomycosis.html Merck Manual: Blastomycosis]
=== Journal Articles ===
* Rooney PJ, Klein BS. [http://www.ncbi.nlm.nih.gov/pubmed/11906450 Linking fungal morphogenesis with virulence]. ''Cell Microbiol'' 2002 Mar;4(3):127-37.
=== Images ===
* [{{SERVER}}/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]
* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]
{{IPLab 10}}
[[Category: IPLab:Lab 10]]
