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File:IPLab2Hypertrophy6.jpg|This gross photograph shows an example of normal physiologic hypertrophy. The organs shown are an open uterus (1), cervix (2) and vagina (3), both ovaries (4) and both kidneys (5) from a woman who died shortly after normal delivery from causes unrelated to childbirth. Note the marked thickening of the uterine wall due to smooth muscle cell hypertrophy.
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== Study Questions ==
* <spoiler text="Is this case of myocardial hypertrophy an example of physiologic or pathologic hypertrophy?">Pathologic.</spoiler>
* <spoiler text="What are some factors that lead to the decompensation of this heart?">The exact mechanism for why hypertrophied hearts go on to develop congestive heart failure is not known. However, some contributing factors may include:
# limitation of the vascular supply to the enlarged myocardial fibers,
# diminished oxidative capabilities of the mitochondria,
# alterations in protein synthesis & degradation, or
# alterations in the cytoskeleton.</spoiler>
== Additional Resources ==
=== Reference ===
* [http://emedicine.medscape.com/article/890068-overview eMedicine Medical Library: Pediatric Hypertrophic Cardiomyopathy]
* [http://emedicine.medscape.com/article/163062-overview eMedicine Medical Library: Heart Failure]
* [http://www.merckmanuals.com/professional/cardiovascular_disorders/cardiomyopathies/hypertrophic_cardiomyopathy.html Merck Manual: Hypertrophic Cardiomyopathy]
* [http://www.merckmanuals.com/professional/cardiovascular_disorders/heart_failure/heart_failure_hf.html Merck Manual: Heart Failure]
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