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File:IPLab6Amyloid11.jpg|This photomicrograph of the tongue demonstrates extensive amyloid deposits (1) separating the skeletal muscle fibers of the tongue. In many cases the amyloid encircles the muscle fibers (2) and these muscle fibers are atrophied.
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== Virtual Microscopy ==
=== Liver: Amyloid H&E ===
<peir-vm>IPLab6Amyloid_HE</peir-vm>
=== Liver: Amyloid Congo Red ===
<peir-vm>IPLab6Amyloid_Congo_Red</peir-vm>
=== Normal Liver H&E ===
<peir-vm>UAB-Histology-00149</peir-vm>
== Study Questions ==
Amyloid is homogeneous, glassy, and pink in appearance; thus, we describe amyloid as having a hyaline appearance.</spoiler>
* <spoiler text=" Is amyloid intracellular or extracellular?">Hyaline is a descriptive histologic term which refers to an alteration within cells or Extracellular.</spoiler>* <spoiler text="What other organs/tissues may be affected in the extracellular space which has a homogeneouspatients with this type of amyloidosis?">Kidneys, heart, gastrointestinal tract, and tongue.</spoiler> == Additional Resources ===== Reference ===* [http://emedicine.medscape.com/article/335414-overview eMedicine Medical Library: Amyloidosis]* [http://emedicine.medscape.com/article/335559-overview eMedicine Medical Library: Amyloidosis, AA (Inflammatory)]* [http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/amyloidosis/amyloidosis.html Merck Manual: Amyloidosis] === Journal Articles ===* Obici L, glassyMerlini G. [http://www.ncbi.nlm.nih.gov/pubmed/22653707 AA amyloidosis: basic knowledge, pink appearance in routine histologic sections stained with hematoxylin unmet needs and eosinfuture treatments]. ''Swiss Med Wkly'' 2012 May 31;142:w13580. === Images ===* [{{SERVER}}/library/index.php?/tags/65-amyloidosis PEIR Digital Library: Amyloidosis Images]* [http://library.med.utah.edu/WebPath/CINJHTML/CINJIDX.html#4 WebPath: Cellular Accumulations] == Related IPLab Cases ==* [[IPLab:Lab 6:Multiple Myeloma|Lab 6: Multiple Myeloma with Amyloid]]* [[IPLab:Lab 6:Senile Amyloidosis|Lab 6: Heart: Senile Amyloidosis]]
{{IPLab 6}}
[[Category: IPLab:Lab 6]]