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21 August 2013
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Created page with " * navigation ** mainpage|mainpage-description ** http://peir.path.uab.edu/library|Digital Library ** IPLab|IPLab ** recentchanges-url|recentchanges ** randompage-url|randompa..."
IPLab:Lab 8:Hepatitis B
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab8HBV1.jpg|This is a low-power photomicrograph of liver from this case. This section was stained with a modified..."
File:IPLab8HBV10.jpg
This high-power photomicrograph of the previous section shows the HBcAg positive nuclei (arrows).
File:IPLab8HBV9.jpg
This is a low-power photomicrograph of the same liver reacted with antibody specific for hepatitis B core antigen (HBcAg). The hepatocytes that contain HBcAg stain brown. Note that even at this low magnification, many brown-staining nuclei can be seen.
File:IPLab8HBV8.jpg
This higher-power photomicrograph of the previous section shows more clearly the HBsAg positive cells (arrows). Upon staining with H&E, these same cells exhibit a "ground glass" appearance, which is due to the accumulation of HBsAg in the hepatocyte cy...
File:IPLab8HBV7.jpg
This is a low-power photomicrograph of liver from the previous image which has been reacted with antibody specific for HBsAg. The hepatocytes that contain HBsAg stain brown.
File:IPLab8HBV6.jpg
This is a photomicrograph of a liver section from another case of hepatitis B. In this H&E-stained section, the typical "ground glass" appearance of the hepatocytes can be appreciated (arrows).
File:IPLab8HBV5.jpg
This high-power photomicrograph showing hepatocytes, the cytoplasm of which contain intracytoplasmic accumulations (arrows) of hepatitis B surface antigen.
File:IPLab8HBV4.jpg
This is a high-power photomicrograph of liver with numerous hepatocytes containing accumulations of magenta-staining material in the cytoplasm (arrows).
File:IPLab8HBV3.jpg
This is a higher-power photomicrograph of the periportal region exhibiting some inflammation and bile duct hyperplasia. There is also congestion and some loss of hepatocytes with disruption of the hepatic cords.
File:IPLab8HBV2.jpg
This is a higher-power photomicrograph of liver from this case. Note the severe congestion (RBCs in sinusoids) and the presence of occasional hepatocytes with dark red/magenta-stained cytoplasm (arrows).
File:IPLab8HBV1.jpg
This is a low-power photomicrograph of liver from this case. This section was stained with a modified aldehyde fuchsin and counterstained with hematoxylin and eosin. Modified aldehyde fuchsin colors cystine-rich proteins--such as HBsAg and elastic fibe...
IPLab:Lab 8:Poliomyelitis
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab8Polio1.jpg|This is a low-power photomicrograph of a section of spinal cord from this case. Note that the anter..."
File:IPLab8Polio5.jpg
This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.
File:IPLab8Polio4.jpg
This is a higher-power photomicrograph taken at the junction of the white and gray matter. Note the inflammatory cellular infiltrate and tissue breakdown. There is significant loss of neurons and myelin in this area.
File:IPLab8Polio3.jpg
This is a high-power photomicrograph of the anterior horn of the spinal cord from this case. Note the absence of motor neurons and the diffuse gliosis.
File:IPLab8Polio2.jpg
This is a higher-power photomicrograph of spinal cord from this case. Note the absence of motor neurons in the anterior horns and the gliosis (arrows).
File:IPLab8Polio1.jpg
This is a low-power photomicrograph of a section of spinal cord from this case. Note that the anterior horns (arrows) are almost completely devoid of neurons.
IPLab:Lab 8:Rabies
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab8Rabies1.jpg|This is a low-power photomicrograph of the hippocampus (arrow) from this case. File:IPLab8Rabies2..."
File:IPLab8Rabies5.jpg
This is a high-power photomicrograph of a neuron surrounded by inflammatory cells (lymphocytes and microglia). This neuron has two intracytoplasmic eosinophilic inclusion bodies (arrows).
File:IPLab8Rabies4.jpg
This is a high-power photomicrograph of neurons containing variably-sized intracytoplasmic eosinophilic inclusion bodies (arrows).
File:IPLab8Rabies3.jpg
This is a higher-power photomicrograph of the shrunken neurons. One neuron appears to have an eosinophilic intracytoplasmic inclusion body (arrow).
File:IPLab8Rabies2.jpg
This is a medium-power photomicrograph of brain tissue exhibiting edema and evidence of shrunken, necrotic neurons (arrows).
File:IPLab8Rabies1.jpg
This is a low-power photomicrograph of the hippocampus (arrow) from this case.
IPLab:Lab 8:HSV Encephalitis
Created page with "== Images == <gallery heights="250px" widths="250px"> IPLab8HSVEncephalitis1.jpg|This is a gross photograph of a section of brain showing multiple small, punctate hemorrhages ..."
File:IPLab8HSVEncephalitis12.jpg
This is a photomicrograph of a brain section stained with an antibody against herpes simplex. Even at this magnification, it is easy to pick out cells that are positive for the virus (arrows).
File:IPLab8HSVEncephalitis11.jpg
This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow).
File:IPLab8HSVEncephalitis10.jpg
This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow). Note that the nuclear chromatin has been pushed to the outer edges of the nucleus.
File:IPLab8HSVEncephalitis9.jpg
This is a high-power photomicrograph demonstrating cells containing intranuclear inclusion bodies (arrows).
File:IPLab8HSVEncephalitis8.jpg
This is a high-power photomicrograph showing several necrotic cells (arrows).
File:IPLab8HSVEncephalitis7.jpg
This is a high-power photomicrograph demonstrating clear areas, which indicate edema, and numerous shrunken red necrotic cells (1). At this power, it can be seen that eosinophilic intranuclear inclusion bodies have displaced chromatin to the periphery ...
File:IPLab8HSVEncephalitis6.jpg
This is another high-power photomicrograph showing a blood vessel with perivascular hemorrhage and mild perivascular lymphocytic cuffing (arrow). In addition, there are numerous red shrunken neurons and glia with pyknotic nuclei throughout this section.
File:IPLab8HSVEncephalitis5.jpg
This is a high-power photomicrograph of the previous section. At this power it is easier to see the blood vessel with the perivascular hemorrhage and mild perivascular lymphocytic cuffing (1). In addition, the areas of edema and loss of neurophil (2) c...
File:IPLab8HSVEncephalitis4.jpg
This is a medium-power photomicrograph showing a blood vessel with perivascular hemorrhage (1), areas with loss of brain parenchyma, and edema (2). Even at this power, it can be seen that many of the cells are shrunken and dark red, suggesting that the...
File:IPLab8HSVEncephalitis3.jpg
This is a low-power photomicrograph showing a section of brain with numerous perivascular hemorrhages (arrows) and some areas that appear hypercellular.
File:IPLab8HSVEncephalitis2.jpg
This is a closer view of the previous section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).
File:IPLab8HSVEncephalitis1.jpg
This is a gross photograph of a section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).
IPLab:Lab 8:HSV Glossitis
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IPLab:Lab 8:HSV Glossitis
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab8HSVGlossitis1.jpg|This is a low-power photomicrograph showing a cross section of the tongue. There is an area ..."
File:IPLab8HSVGlossitis5.jpg
This is a high-power photomicrograph of epithelium near the edge of the ulcer. The cells that have been invaded by the herpes virus contain intranuclear accumulations of amphophilic viral inclusions (arrows).
File:IPLab8HSVGlossitis4.jpg
This is a higher-power photomicrograph of epithelium at the edge of the ulcer. Amphophilic intranuclear inclusion bodies can be seen in almost all of the epithelial cells in this section.
File:IPLab8HSVGlossitis3.jpg
This is a medium-power photomicrograph of epithelium at the edge of the ulcer. Even at this power, amphophilic (dark, blue-purple-staining) intranuclear inclusion bodies can be seen in the epithelial cells. Note the inflammatory infiltrate in the subep...
File:IPLab8HSVGlossitis2.jpg
This higher-power photomicrograph shows the epithelium (1), the edge of the ulcer (2), and the ulcerated epithelium (3). There is an inflammatory exudate at the base of the ulcer and some necrotic cells where the epithelium once was present.
File:IPLab8HSVGlossitis1.jpg
This is a low-power photomicrograph showing a cross section of the tongue. There is an area along the surface of the tongue where the normal epithelium has been lost and there are areas of ulceration (arrows).
IPLab:Lab 7:Osteosarcoma
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab7Osteosarcoma1.jpg|This is a photograph of the patient prior to surgery. Note the marked swelling of the knee. ..."
File:IPLab7Osteosarcoma15.jpg
This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology and multiple mitotic figures (arrows).
File:IPLab7Osteosarcoma14.jpg
This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.