IPLab:Lab 5:Gaucher Disease

Images

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  This is a gross photograph of spleen from this case. The spleen is enlarged and the surface is finely granular.

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  This is a cut section of spleen from this case. Again note the fine granular appearance to the tissue.

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  This is a low-power photomicrograph of normal spleen (left) and the spleen from this case (right). The loose appearance of the tissue in the Gaucher spleen is due to artifactual loss of tissue during histologic processing.

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  This is a photomicrograph of the spleen from this case. There is very little if any white pulp evident in this section.

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  This is a higher-power photomicrograph of the spleen from this case. Again there is no white pulp and the red pulp is filled with large eosinophilic cells.

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  This is another high-power photomicrograph of the spleen from this case. At this power it is easier to see the large eosinophilic cells.

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  This is another high-power photomicrograph of the spleen from this case. At this high power individual cells can be better appreciated.

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  This is a higher-power photomicrograph of the spleen from this case. At this higher power individual cells can be better appreciated and the fibrillar nature of the eosinophilic cytoplasmic material can be seen.