Cytologically Yours: Unknowns: 201312: Case 1

Contents

Clinical History

81 year old female. Right breast FNA, ThinPrep.

Cytology

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Resident Questions

• Diagnosis?

• Cytology diagnosis: Breast carcinoma
• Surgical diagnosis: Invasive ductal carcinoma

Surgical Pathology

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Cytologic Features

• Discohesion
• Pleomorphism
• Nuclear irregularity
• Abnormal chromatin pattern
• Irregular, large nucleoli
• Absence of myopeithelial cells
• Intracytoplasmic lumens