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→Virtual Microscopy
== Autopsy Findings ==
There were petechia and ecchymoses all over the body. The skin on the hands, feet, and in patches over the entire body was deep purple, the epidermis was friable and there were large areas of desquamation. The fingertips and toes were black and dry. The liver had large areas of pale softened tissue indicative of liver necrosis.
File:IPLab12Acetaminophen8.jpg|This is a higher-power photomicrograph of the skin from this patient showing a blister and the thrombosed small vessels (arrows) in the dermis.
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== Virtual Microscopy ==
=== Liver: Acetominophen Toxicity ===
<peir-vm>IPLab12Acetaminophen</peir-vm>
=== Normal Liver ===
<peir-vm>UAB-Histology-00149</peir-vm>
== Study Questions ==
=== Journal Articles ===
* Schiødt FV, Lee WM, Bondesen S, Ott P, Christensen E. [http://www.ncbi.nlm.nih.gov/pubmed/11929388 Influence of acute and chronic alcohol intake on the clinical course and outcome in acetaminophen overdose]. ''Aliment Pharmacol Ther'' 2002 Apr;16(4):707-15.* Yeates PJ, Thomas SH. [http://www.ncbi.nlm.nih.gov/pubmed/10606832 Effectiveness of delayed activated charcoal administration in simulated paracetamol (acetaminophen) overdose]. ''Br J Clin Pharmacol'' 2000 Jan;49(1):11-4.
=== Images ===
* [{{SERVER}}/library/index.php?/tags/2169-acetaminophen_toxicity PEIR Digital Library: Acetaminophen Toxicity Images]* [http://library.med.utah.edu/WebPath/LIVEHTML/LIVERIDX.html WebPath: Hepatic Pathology]
== Related IPLab Cases ==